Choosing the right work backpack matters because you carry more than a laptop — you carry tools, snacks, chargers and sometimes patient essentials. If you want a bag that keeps things organized, protects tech, and is comfortable during long shifts, this guide helps you narrow the options so you spend less time digging and more time doing. Below you’ll find picks that balance durability, organization, comfort and price so you can pick a nurse-ready backpack that fits your day.
Top Picks
| Category | Product | Score |
|---|---|---|
| 🏆 Best Overall | 96/100 | |
| 🚀 Most Durable | 93/100 | |
| 🔒 Best Anti-Theft | 90/100 | |
| 🧭 Best For Travel | 94/100 | |
| 💰 Best Budget | 87/100 | |
| 🌧️ Best Waterproof | 95/100 | |
| 🎨 Most Stylish | 91/100 | |
| 🧰 Best Clinical | 89/100 | |
| 🔧 Best Structured | 88/100 | |
| ⭐ Most Charming | 85/100 |
How We Picked These Backpacks
You want a bag that makes your shift easier. We focused on what matters most to nurses: organization (easy access pockets for pens, stethoscope and meds), protection (padded laptop sleeves and water resistance), comfort (padded straps and balanced load), and real-world durability.
We also considered special features that save you time — insulated lunch compartments, wide framed openings that let you see contents, USB charging ports, anti-theft pockets and price. Finally, we weighed user feedback so you get options that have held up in clinical and travel use.
You get a two-in-one bag that lets you carry your laptop and your lunch without juggling two separate items. The bottom section is a removable, insulated lunch compartment that folds away when you need more space, while the main compartment has a padded 15.6-inch laptop sleeve, plenty of pockets for pens, a stethoscope or clipboard, and elastic side holders for a water bottle and umbrella. The built-in USB port gives you easy access to charge on the go (you pop a power bank inside), and the breathable padded straps make long shifts or commutes more comfortable. It works great for daily nursing shifts, school, or travel days when you want to keep food separate from tech — if you want one bag that does both jobs without looking bulky, this is a practical pick.
What People Say
Customers commonly praise how organized the bag is — lots of pockets, a laptop sleeve, and a practical lunch compartment that really keeps food cool or warm for hours. People also like the USB charging port and comfortable straps for long shifts.
A few mention concerns about zipper or stitch durability and that the lunch area can be a bit snug with larger containers.
Overall Sentiment: Positive

Brand Trust
ETRONIK has built a solid reputation on this model thanks to many positive reviews and consistent features, though a small number of users report stitching or zipper issues over time.
Travel Ready
Very travel-friendly for commuting and short trips — laptop protection, insulated food storage, and pockets to keep essentials handy.
Top Benefits
- Detachable insulated lunch compartment for fresh meals
- Padded 15.6-inch laptop sleeve and organized pockets
- External USB charging port for on-the-go power
- Comfortable, breathable shoulder straps for long wear
Rating: 4.6 (total: 5,330+)
You get a surprisingly roomy, stylish bag that’s built for real life — from hectic nursing shifts to weekend travel. The wide steel-frame top makes it easy to see and grab what you need (no digging around), while a padded rear sleeve keeps a 15.6-inch laptop tucked away and protected.
There are dozens of pockets for pens, snacks, chargers and small medical tools, plus elastic side pockets for bottles and a luggage strap that slides over a suitcase handle when you’re on the move. It’s lightweight at about 2 lbs and the breathable padded straps help on long days; just note the structured top and size can feel a bit large if you need a slim personal item on a strict flight. If you want a practical, polished bag that balances organization with a professional look, this is a solid choice.
What People Say
Customers frequently mention how organized and roomy this backpack is — the many pockets and the wide opening make packing and finding items easy. Reviewers also like the padded laptop sleeve, water-resistant material and comfortable straps for long shifts.
A few users point out that the structured top and size can be bulky for strict airline personal-item rules, and some note minor issues like snaps or single zippers needing careful use.
Overall Sentiment: Positive

Brand Trust
LOVEVOOK comes across as reliable for this model, with a lot of positive feedback, a one-year warranty and practical features that match what buyers expect. A small number of users report minor durability or hardware annoyances over time.
Travel Ready
Good for commuting and short trips thanks to the luggage strap, bottle pockets and protective laptop compartment, though the firm top and larger size may be too bulky for some strict carry-on rules.
Top Benefits
- Wide steel-frame opening for easy access
- Padded rear compartment for a 15.6-inch laptop
- Extensive organization with multiple pockets (22)
- Luggage strap and side bottle pockets for travel
- Ergonomic padded straps for comfortable all-day wear
- Waterproof, tear-resistant nylon with leather accents
Rating: 4.8 (total: 792+)
You get a roomy, stylish backpack that actually makes busy days easier. The wide steel-frame top opens flat so you can see everything at once — handy when you need supplies fast during a shift.
There’s a padded sleeve for a 15.6″ laptop plus a tablet pouch, about 15 pockets for pens, chargers and small medical tools, and side bottle pockets with retractable S-ring straps to secure a large tumbler. The quilted puffer front and breathable padded straps keep it comfortable on long commutes, and the luggage strap and rear anti-theft pocket make travel simpler. It’s light enough for daily wear but substantial enough to double as an overnight or carry-on-friendly bag if you’re not tightly limited by strict personal-item rules. If you want a practical, organized bag that still looks put-together for work or weekend trips, this is a dependable pick.
What People Say
Most buyers praise how organized and roomy the bag is — the many pockets and wide opening make it easy to pack and find things quickly. People also appreciate the padded laptop sleeve, sturdy zippers, the bottle-holder design and the comfy straps for long days. A few mention the structured top and overall size can feel bulky if you need a very small personal item on a plane, and isolated reports note minor hardware wear over long-term heavy use.
Overall Sentiment: Positive

Brand Trust
LOVEVOOK shows consistently positive feedback for this model, with lots of users reporting good build quality and practical features. A small number of shoppers mention minor durability or hardware quirks after heavy use, but overall impressions lean reliable.
Travel Ready
Good for commuting and short trips thanks to the luggage strap, protective laptop sleeve and secured bottle pockets; the firm top and larger footprint can be a drawback if you need the smallest possible personal item on certain flights.
Top Benefits
- Wide steel-frame opening for quick access
- Padded rear sleeve fits a 15.6-inch laptop
- About 15 pockets for neat organization
- Side pockets with S-ring straps for large bottles
- Luggage strap and rear anti-theft pocket for travel
- Breathable padded shoulder straps and lightweight feel
- Wipe-clean, water-resistant puffer exterior
Rating: 4.8 (total: 169+)
You get a roomy, work-ready backpack that keeps your shift essentials organized without feeling bulky. The wide-open main compartment and a handful of internal and external pockets make it easy to stash folders, nursing notes, a tablet and a water bottle, while a padded sleeve fits a 15.6″ laptop for those days you bring a computer. The straps are breathable and reinforced, so it stays comfortable on long commutes, and the waterproof exterior helps protect supplies when weather or spills happen. There’s a built-in USB port for on-the-go charging when you pair a power bank, and the clean, professional look works for clinical days, nursing school or quick overnight trips.
If you want a practical, fuss-free bag that still looks tidy on the floor at work, this one’s worth considering.
What People Say
Reviewers consistently highlight how spacious and well organized the bag is, noting the pockets and wide opening make it easy to get to supplies during busy shifts. Many people compliment the build quality and comfortable straps, and they appreciate the waterproof fabric and laptop capacity. A few shoppers mention the USB port may require you to provide your own cable or power bank and that the look or size isn’t to everyone’s taste, but overall opinions skew very positive.
Overall Sentiment: Positive

Brand Trust
Srotek receives mostly favorable feedback for this model, with buyers reporting solid construction and practical features. A small number of users point out minor quibbles like accessory cords or personal fit, but overall the product appears reliable for everyday nursing use.
Travel Ready
Good for commuting, clinical rotations and short overnight trips thanks to the laptop sleeve, roomy compartments and water-resistant material. It’s a practical carry for work and can double as a compact travel bag, though you may want to bring a separate power bank cable for the USB port.
Top Benefits
- Wide main opening and multiple pockets for fast organization
- Padded sleeve fits a 15.6-inch laptop
- Built-in USB charging port for on-the-go top-ups
- Breathable, reinforced shoulder straps for long shifts
- Waterproof exterior protects gear from spills
- Durable stitching at handles and straps for everyday use
- Available in several styles and colors suited to nurses
Rating: 4.7 (total: 40+)
You get a surprisingly roomy, no-nonsense bag that was clearly designed with busy clinicians in mind. There’s a padded sleeve for a 15.6″ laptop, a removable medical supplies organizer that snaps into the main compartment, and lots of dedicated pockets for pens, scissors and small tools so things don’t end up in a jumbled mess. The material is water-resistant and easy to wipe clean, the shoulder straps are well padded and breathable, and a luggage strap lets you slide the pack over a suitcase handle on travel days.
Take the organizer out and it doubles as a tidy work or travel backpack for weekend trips or clinical rotations. If you want a durable, practical bag that keeps your shift gear accessible and sane, this one’s a solid pick.
What People Say
Buyers frequently praise how much it holds and how organized it keeps medical supplies, noting the removable organizer and plentiful pockets make shift life easier. People also like the padded straps and water-resistant fabric for everyday wear and messy environments.
A few users mention the side bottle pockets don’t always secure very large bottles and some would prefer chest or compression straps for heavy loads, but overall feedback is strongly favorable.
Overall Sentiment: Positive

Brand Trust
MATEIN is generally seen as a dependable brand for practical backpacks—customers report solid construction, durable zippers and consistent performance over months of use. A small number of buyers report minor fit or pocket-size quirks, but most feel the bag delivers reliable value for clinical work.
Travel Ready
Travel-friendly: the luggage strap, roomy compartments and laptop sleeve make it a handy carry-on or overnight bag for rotations and short trips, though you may want a chest strap for longer hauling.
Top Benefits
- Removable medical supplies organizer keeps clinical kit tidy
- Padded 15.6-inch laptop sleeve for on-shift computing
- Multiple internal pockets and elastic pen slots for easy access
- Water-resistant fabric that wipes clean
- Comfortable breathable shoulder straps and padded back
- Luggage strap for easy commuting and short trips
- Front anti-theft pocket and side elastic pockets for quick items
Rating: 4.7 (total: 1102+)
You’ll find a surprisingly organized, professional-looking pack that was designed with shift life in mind. It has a padded sleeve that fits a 15.6″ laptop, a hard EVA stethoscope case tucked away for protection, and a USB port so you can route a power bank inside and top up devices on the go.
The wide-open zipper and multiple pockets make loading and unloading easy during busy shift changes, and the invisible luggage strap plus anti-theft pocket are handy when you’re commuting or traveling. It’s structured enough to stand upright on a counter but still stylish for everyday wear — a solid choice if you want a bag that keeps tools and tech tidy without looking like a utility sack.
What People Say
Shoppers commonly praise how many pockets and compartments there are and how the bag keeps nursing supplies and tech organized. Many appreciate the hard stethoscope case and the structured, upright shape, and people often call out the convenience of the USB port—though they note you need to use your own power bank. A few users mention the metal-framed opening adds weight or that the 15.6″ size can be snug for larger laptops, but overall feedback is very favorable.
Overall Sentiment: Positive

Brand Trust
LOVEVOOK is viewed as a practical brand for everyday backpacks—customers report sturdy construction and reliable zippers that hold up under heavy use. A minority note fit or sizing quirks and occasional wear after intensive years of use, but most feel the bag offers dependable value for clinical and daily wear.
Travel Ready
Travel Ready: the luggage sleeve, anti-theft pocket and organized compartments make it handy for commuting and short trips, though the structured frame can add weight when you’re packing heavy.
Top Benefits
- Hard EVA stethoscope case protects delicate gear
- Padded sleeve fits most 15.6-inch laptops and tablets
- USB charging port for convenient device top-ups with a power bank
- Anti-theft pocket and invisible luggage strap for safer commuting
- Wide-open zipper and organized pockets for quick access
- Durable polyester construction that wipes clean
- Structured design helps the bag stand upright on surfaces
Rating: 4.6 (total: 2028+)
You’ll notice this pack was built for shift life. The steel-frame top helps the bag keep its shape so you can open it wide and grab supplies without everything collapsing inside, and the padded 15.6″ laptop layer plus cushioned interior protect tech when you’re on the move.
There’s room for A4 folders, sanitizers and bandages in the main compartment, plus smaller internal pockets for masks, stethoscopes and pens. Outside, elastic side pockets hold a bottle or umbrella and front/back zip pockets keep things you need fast within reach.
The padded straps and a snap-secured top handle make it comfortable for long shifts or quick home-visit runs. If you want a structured, practical bag that organizes both medical tools and everyday items, this one’s a sensible pick.
What People Say
You’ll see a lot of shoppers appreciate how much this bag holds without feeling bulky and praise the organized pocket layout that keeps nursing supplies tidy. Many like the padded laptop layer and the framed opening that helps the bag stay upright, and people frequently note the comfortable straps and sturdy stitching. A smaller group mention they wanted a larger overall size or that small plastic fittings can wear over many years of daily use.
Overall Sentiment: Positive

Brand Trust
LoDrid comes across as a brand that focuses on functional, colorful designs; most buyers report solid construction, dependable zippers and good stitching for daily clinical use. A few users have noted wear on small plastic parts after extended heavy use, but overall impressions lean toward reliable value.
Travel Friendly
Travel Friendly: the padded laptop pocket, upright frame and organized pockets make it handy for commuting and short trips. The steel frame adds structure but can feel a bit heavier if you pack it very full.
Top Benefits
- Steel-frame top keeps the bag open and upright for easy access
- Padded sleeve fits most 15.6″ laptops and protects devices
- Spacious main compartment fits A4 folders and medical supplies
- Multiple inner pockets for masks, stethoscopes, cotton swabs and small tools
- External elastic side pockets for water bottle or umbrella
- Padded shoulder straps and snap-secure handle for comfortable carrying
- Durable nylon construction with a structured silhouette
Rating: 4.6 (total: 559+)
If you need a bag that keeps your shift life organized, this one makes it easy. You get a roomy 20L main area, two compartments and about a dozen pockets that help you separate tech, charts and medical supplies so nothing gets lost mid-shift.
The padded sleeve fits most 15.6″ laptops and the wide-open top layout means you can grab supplies fast during rounds or home visits. It’s made from lightweight, water-resistant polyester with reinforced seams and thicker shoulder straps, so it carries more comfortably than a typical tote. If you want a practical, cute-looking backpack that doubles as a clinical bag and a commuter pack, this is a sensible pick.
What People Say
Most shoppers like how much this backpack holds without feeling bulky, and they often highlight the many pockets and the dedicated laptop sleeve as big wins for work and school. People also appreciate the water-resistant fabric and comfortable straps for home visits or commuting.
A minority mention zipper failures or that some parts feel less durable after heavy daily use.
Overall Sentiment: Positive

Brand Trust
Gatycallaty comes across as a value-minded brand: buyers often praise the thoughtful layout and practical materials, though a few users report occasional quality-control hiccups like weaker zippers. Overall it’s seen as a budget-friendly option that delivers useful features.
Travel Friendly
Good for commuting and short trips—fits a 15.6″ laptop, stays lightweight, and the organized pockets make moving between home visits and the clinic easier; avoid overpacking to protect zippers and seams.
Top Benefits
- Roomy 20L capacity holds supplies, folders and a 15.6″ laptop
- Two main compartments plus 12 pockets for sensible organization
- Lightweight, water-resistant polyester protects contents on rainy shifts
- Thick shoulder straps and reinforced seams for everyday carry
- Wide-open main compartment for quick access during rounds
- Multiple small pockets keep pens, stethoscope and masks tidy
- Designed to work as both a clinical bag and a commuter backpack
Rating: 4.5 (total: 51+)
If you want a hardworking everyday backpack that also travels well, this one does a lot right. You get a roomy 30 L capacity, a padded adjustable sleeve for laptops up to 15.6″ and a doctor-bag style top that makes seeing and grabbing what you need quick and painless during a busy shift.
The layout is built for organization — exterior quick-access pockets, internal mesh and pen holders, a charging port pocket and even a luggage strap so you can slide it over your suitcase handle at the airport. The straps and back padding help with comfort when you’re carrying gear between home, clinic or a long shift, though it can feel heavy if you stuff it full of dense items. For nurses who need pockets for pens, a stethoscope and a tablet, plus room for a change of clothes or lunch, this is a reliable, practical pick you can use daily and on short trips.
What People Say
People commonly praise how much this backpack holds while still looking neat and professional, and many call out the organization — lots of pockets and a proper laptop sleeve — as a major strength. Users also appreciate travel-friendly touches like the luggage strap and charging port, though a few note it can feel heavy when fully loaded and that occasional small quality issues (zips or snaps) appear after heavy daily use.
Overall Sentiment: Positive

Brand Trust
Hap Tim is seen as a value-oriented brand that focuses on practical features. Buyers often point to thoughtful pockets, useful travel extras and generally reliable construction, while a small number mention isolated durability concerns.
Overall it reads as a brand that delivers useful designs for everyday needs.
Travel Friendly
Very usable for commuting and short trips — it fits under an airplane seat, has a luggage strap and organized pockets for chargers and travel essentials. Keep in mind the top zippers are exposed, so you may want an umbrella in heavier rain and avoid overpacking to keep straps and zippers working well.
Top Benefits
- 30 L capacity fits work supplies, a change of clothes and a 15.6″ laptop
- Adjustable padded laptop sleeve protects devices against movement
- Doctor-bag style wide opening for fast access to supplies
- Multiple pockets and organizers for pens, chargers and small tools
- Luggage strap makes airport and train travel easier
- Durable water-resistant exterior keeps contents safer in light rain
- Padded back and shock-absorbing straps improve carrying comfort
Rating: 4.7 (total: 6513+)
If you need a bag that keeps you organized during long shifts and still looks polished for off-duty life, this one’s worth a look. It holds a 15.6″ laptop in a padded sleeve, has a wide, framed top opening so you can see everything at a glance, and offers about 2 roomy compartments plus lots of smaller pockets for pens, chargers and small tools.
Travel-friendly touches like a luggage strap, an external USB port and a hidden back pocket make commuting or plane trips easier, and the water-resistant polyester helps protect your stuff from light rain. It’s a practical everyday companion for nurses who want pockets for stethoscopes and pens, plus room for a change of clothes or snacks — just try not to overpack so the straps stay comfortable.
What People Say
Customers often highlight how much this backpack holds without feeling bulky and praise the organization — lots of pockets, a solid laptop sleeve and handy travel extras like the luggage strap and USB port. Many also call out the sturdy zippers, framed top that stays open for easy access, and overall build quality, while a few mention minor quirks like the bag leaning forward when heavily loaded or occasional small hardware issues after long daily use.
Overall Sentiment: Positive

Brand Trust
LOVEVOOK is viewed as a value-focused brand that delivers practical, fashion-forward designs. You’ll see plenty of buyers appreciating the thoughtful pockets and travel features, and the brand backs products with a warranty and responsive customer support; a small number of users report isolated durability niggles but overall trust the brand for everyday gear.
Travel Friendly
Very travelable for commuting and short trips — it’s sized to fit under a plane seat, has a luggage strap to secure it to a suitcase, and the USB port and organized pockets make charging and access simpler when you’re on the move. The water-resistant fabric helps in light rain, though you may want additional cover in heavy downpours and avoid overstuffing to keep straps comfortable.
Top Benefits
- Fits up to a 15.6″ laptop in a padded compartment
- Wide, framed top opening for quick access and visibility
- Multiple internal and external pockets for pens, devices and small gear
- Built-in USB charging port for on-the-go power
- Hidden anti-theft pocket keeps valuables safer
- Luggage strap for slipping over a suitcase handle
- Water-resistant polyester exterior and reinforced seams for everyday wear
Rating: 4.7 (total: 31228+)
FAQ
How Do I Choose The Best Backpack For Nursing Shifts?
Think about what you carry every shift and choose a bag that matches that load: if you bring a laptop and charting tablet, look for a padded sleeve sized for 15–16 inches; if you pack lunch, an insulated bottom compartment or removable cooler keeps food separate. Prioritize comfort and support by checking padded shoulder straps, a ventilated back panel and a sternum or waist strap for longer commutes. Material matters: water‑resistant fabric and sturdy zippers stand up to daily spills and cleaning.
Features to weigh are a wide framed opening for fast access, dedicated pockets for pens and scissors, a secure pocket for valuables, an external USB port if you want on‑the‑go charging, and a luggage sleeve if you travel between sites. Finally, match size to your commute — a slimmer, highly organized pack if you walk or use public transit, or a slightly larger, more structured bag if you drive and need to carry extra gear.
Will A Nursing Backpack Keep My Electronics And Lunch Safe And Separate?
Yes, many nurse backpacks are designed with separate compartments so you can protect electronics and food: a padded laptop sleeve isolates your device from the main compartment while an insulated, removable lunch pocket or cooler sits in the bottom to prevent leaks touching electronics. Use leakproof containers and put perishables in a sealed bag before placing them in the insulated section, and keep chargers and power banks in a small internal pocket when you use an external USB port.
For extra protection, carry electronics in a sleeve and store important items in a hidden anti‑theft pocket or inner zip to reduce the chance of spills or snags during busy shifts.
How Do I Care For And Pack A Nurse Backpack To Stay Organized And Comfortable?
Pack heavier items close to your back and distribute weight evenly so the pack sits high and stable; put frequently used tools in top or external pockets for quick access and keep small items in labeled pouches to avoid digging. Clean the bag regularly by wiping water‑resistant fabrics with mild soap and air drying, remove and air out the lunch insert after use, and inspect seams and zippers for wear to avoid surprises.
Adjust straps so the shoulder pads sit comfortably on your shoulders and consider using a chest strap for long shifts. Small habits — empty the bag nightly of food and linens, recharge power banks separately, and replace or resew worn straps promptly — will extend the life and usefulness of your backpack.
What Nurses Prefer
When choosing between the ETRONIK Lunch Backpack, LOVEVOOK Laptop Backpack, and LOVEVOOK Puffer Laptop Backpack, you typically prioritize organization and functionality — insulated compartments and easy-access pockets for meals and meds, padded laptop sleeves and protective padding for devices, plus durable, water-resistant materials and easy-to-clean surfaces. Comfort and style matter too, so you look for cushioned straps, lightweight build, and a professional or cozy aesthetic that fits your shifts.

Wrapping Up
A good nursing backpack should save you time and protect your essentials so you can focus on patients and shifts. From the framed, wide-open designs that make organization simple to waterproof, padded laptop pockets and insulated lunch compartments, these picks cover common needs. Choose a bag with a layout that matches how you work — if you bring a laptop and charts, prioritize a padded sleeve and structure; if you move between homes or wards, look for water resistance and comfortable straps; if you carry a lot of small tools, pick a bag with many targeted pockets.
Use the categories above to match a pack to your routine and budget so you get a reliable daily companion that lightens your load.
| Product | Image | Rating | Product Dimensions | Item Weight | Storage Capacity |
|---|---|---|---|---|---|
| ETRONIK Lunch Backpack |
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4.6/5 (5,330 reviews) | 14.17 x 9.45 x 3.15 inches | 2 pounds | 23 liters |
| LOVEVOOK Laptop Backpack for Women |
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4.8/5 (792 reviews) | 7.5 x 12.5 x 16.5 inches | 2 pounds | N/A |
| LOVEVOOK Puffer Laptop Backpack |
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4.8/5 (169 reviews) | 1 x 2 x 2 inches | 1.81 pounds | 1 liter |
| Nurse Backpack / Bag for Women |
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4.7/5 (40 reviews) | 1 x 1 x 1 inches | 1 pound | 1 liter |
| MATEIN Nurse Backpack |
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4.7/5 (1,102 reviews) | 7.09 x 11.81 x 16.93 inches | 2.2 pounds | N/A |
| LOVEVOOK Nurse Backpack Laptop Backpack |
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4.6/5 (2,028 reviews) | 12.5 x 8 x 16 inches | 2.38 pounds | 24 liters |
| LoDrid Nurse Bag |
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4.6/5 (N/A) | 6 x 12 x 16 inches | 1.9 pounds | N/A |
| Gatycallaty Nurse Backpack |
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4.5/5 (51 reviews) | 8 x 12.4 x 17 inches | 1.83 pounds | 20 liters |
| Hap Tim Laptop Backpack |
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4.7/5 (6,513 reviews) | 7.87 x 13.39 x 16.54 inches | 1.5 pounds | 30 liters |
| LOVEVOOK Laptop Backpack |
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4.7/5 (31,228 reviews) | 1 x 1 x 1 inches | 8 ounces | N/A |
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